Marc Sindou (MD, DSc, DHC) is Professor-Emeritus at University of Lyon, France. He was one of the Founding members of the International Association for the Study of Pain. He was President of the World Society for Stereotactic and Functional Neurosurgery. He was awarded: The European Lecture by the European Association of Neurological Societies, the Spiegel and Wycis Medal by the WSSFN, the Award of the Ten Masters in Neurosurgery by the World Federation of Neurosurgical Societies, the Award of Top-neurosurgeon for Cranial Nerve Disorders. Over a forty-year experience he performed six-thousands, open and percutaneous, neurosurgical procedures for Trigeminal Neuralgias.Andrei Brinzeu (MD, PhD, MSc) is Professor of Neurosurgery at the University of Medicine and Pharmacy “Victor Babes” in Timisoara, Romania, where he leads a program in Neurosurgery, Basic Neurosciences, Clinical Neurophysiology and Pain Therapy. He delivered twelve original research publicationsin major international journals on Pain surgery and Cranial nerve dysfunction syndromes, especially on Trigeminal Neuralgia. Dr. Brinzeu particularly worked on the Anatomy of the Cranial Nerves and the Factors influencing outcome of Micro-Vascular Decompression, for which he was Invited-speaker in several International meetings.